A prologue is generally not compulsory for a novel. Its job is to introduce a tidbit of the relevant background of the novel. If your prologue held enough significance to influence how the audience will feel about your novel or a major character in your novel then it should not be there in the prologue. It should be woven into one of the official chapters.
Technically, your audience should already understand what your novel is about and whether they should jump into it just by reading the synopsis. The prologue could be considered a demo run to showcase how well you craft the words, construct the verses, and set the mood. It was like a taste test before you are 100% sure you like this ice cream flavour or not.
Overall, I can not tell you how you should structure your novel but for me the general rule is that "anything that is important to the novel will be found in the official chapters". This means there should be nothing too important in the interlude, epilogue, prologue, bonus chapter, or any other extra materials that isn't the official chapters. Everything the readers need to read start with the first line of chapter 1. That is how I structure my novel. If I couldn't capture the audience with my chapter 1, I did something wrong, or it was not the readers' cup of tea.
Frankly I want my chapter 1 actually has some meaning. It is titled chapter 1 so people should be able to look at it and tell that "this here is where the story begins".
I will not speak for other authors.