Depends on what kind of comedy you're writing. If the comedy is monologue, 1st would probably be the best. If it's a manzai, 3rd would probably work best.
If the comedy is satire, 2nd is probably better.
1st person: Shit! How could I have just pooped! Damn you, asshole!
2nd person: So you were talking to the cute maid at the cafe, and then suddenly it hits you. And you told her, "Sorry, I just pooped."
3rd person:
Person A: I was busy laying down the cards, talking about some amazing thing I did, when suddenly...
Person B: What happened?
Person A: I said, "Sorry, I just pooped."
Person B: [smacks Person A's head] That's not something you tell people, moron!